COMPARATIVE MEDICINE
Classical in vivo models have obvious translational limitations.
Natural diseases in dogs and cats share
numerous features with human diseases.
Why using dogs and cats models?
To establish a continuum between species in terms of
pharmacology, pharmacokinetics and toxicology
in order to reach clinical trials in humans with more reliability.
Comparative Medicine Studies of owned-Dogs with spontaneous cancers, or chronic diseases, as natural animal models for assessment of drug candidates under development for Human Health.
Getting access to more predictive data of Human Cancers (Efficacy, MoA, Immune-Monitoring, Pk/Pd, Therapeutic Scheme, specific Anti-Metastatic effect, new Indication opportunities…) for a more relevant development in clinic in Human.
Late Preclinical stage & early Clinical stage
Main cancers affecting owned-Dogs: NH Lymphoma, Melanoma, Soft tissues sarcoma, Head & Neck Carcinoma, Osteosarcoma, Urogenital tumors, Mammary tumors, Brain & Spinal cord tumors, Prostatic tumor …
Others therapeutic fields : Inflammation, Neurology, Pain, Dermatology, Cardiology, Ophthalmology, Antibiotic resistance…
Imaging (CT-scan, MRI, Scintigraphy), Radiation therapy (High & Low energy), Surgery, Nuclear medicine capabilities, IHC Ventana Discovery capabilities (cross-reactivity step if required before going to Dog patients)
Large team of specialized veterinarians (Oncologists, Cardiologist, Internal Medicine specialists, Imaging specialists, Pathologists, Surgeons, Radiation oncology specialist…) thanks to a network of 25 vet clinical centers across Europe.
